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Jinse Finance reported that the international crude oil futures settlement prices surged by 4.7%. WTI crude oil futures for the April contract rose by 4.67%, closing at $74.56 per barrel; Brent crude oil futures for the May contract increased by 4.71%, closing at $81.4 per barrel.

Vitalik Buterin stated on social media that concerns about the expansion of government and corporate power, loss of privacy, and disorder on social platforms are intensifying, while Ethereum's role in improving real life remains limited. He suggested that Ethereum should become part of building "sanctuary technology," providing users with robust spaces for collaboration and value management through open-source and decentralized technology, rather than simply focusing on finance or pursuing "disrupting the world." Vitalik emphasized that the core of Ethereum is to create "ownerless shared digital spaces," supporting long-term digital arrangements such as multi-signature, markets, and governance structures, and cooperating with the broader ecosystem to enhance resilience.

The executive predicts that after a brief period of slight sales decline, this blockbuster drug will soon return to a strong growth trajectory. This metaphor vividly illustrates Keytruda's development path after its patent protection expires. Contrary to the widespread concerns about the impact of biosimilars, Merck's management demonstrates confidence in product lifecycle management. They expect only a moderate sales pullback, followed by a recovery driven by market expansion and indication broadening. Industry analysis points out that as the world's best-selling PD-1 inhibitor, Keytruda's market position is difficult to fully replace in the short term. Even facing patent expiration, the drug's core role in treatment guidelines for multiple cancer types, as well as Merck's established and comprehensive market system, will provide strong support for its performance.