TBIO Stock: A Guide to Telesis Bio, Inc.
TBIO stock refers to the equity of Telesis Bio, Inc., a prominent player in the synthetic biology sector known for its automation of DNA and mRNA synthesis. Formerly known as Codex DNA, Inc., the company rebranded in November 2022 to better reflect its expanding technological suite. As of late 2024, the stock has undergone significant structural changes, moving from the Nasdaq Global Market to the Over-the-Counter (OTC) markets, which impacts its liquidity and accessibility for retail investors.
Corporate History and Evolution
From Codex DNA to Telesis Bio
Founded in 2011, the company initially gained recognition under the name Codex DNA. It focused on commercializing the Gibson Assembly® method, a staple technique in molecular biology labs worldwide. In November 2022, the company officially changed its name to Telesis Bio, Inc. to align with its vision of providing end-to-end solutions for genomic synthesis.
Stock Listing Status
Historically, TBIO was listed on the Nasdaq. However, following a series of financial challenges and a decline in market capitalization, the company transitioned to the OTC Markets (Ticker: TBIO) in late 2024. According to Stock Analysis data as of late 2024, the company’s market cap has fallen below $100,000, reflecting a high level of volatility and risk often associated with micro-cap stocks in the biotechnology space.
Core Technology and Products
Telesis Bio is recognized for decentralizing the synthesis of genetic material, allowing researchers to build DNA and mRNA on their own benchtops rather than outsourcing to centralized service providers.
The BioXp™ System
The flagship BioXp™ 3250 and 9600 systems are fully automated workstations. These platforms enable the rapid synthesis of genes, clones, and libraries, significantly shortening the design-build-test cycle for pharmaceutical and academic researchers.
Gibson Assembly® and Gibson SOLA
The company owns the proprietary rights to the Gibson Assembly® method, a gold standard for joining multiple DNA fragments. They also developed Gibson SOLA (Systemic Oligonucleotide Linear Assembly), which powers their enzymatic DNA synthesis processes, providing high fidelity and speed.
Financial Performance and Market Stats
The financial health of TBIO has been a point of concern for investors. Based on Yahoo Finance reports, the stock has seen a historical price performance decline of over 99% over a five-year period.
- 52-Week Range: $0.01 - $5.17 (reflecting extreme volatility).
- Revenue: Historically ranging between $17M and $27M annually, though offset by significant net losses due to high R&D costs.
- Market Position: Classified within the Healthcare sector and the Medical Devices/Biotechnology industry.
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Strategic Partnerships
Despite its stock performance, Telesis Bio has maintained critical industry relationships. A notable collaboration includes Beckman Coulter Life Sciences, where the two entities worked to integrate BioXp™ synthesis capabilities into larger laboratory automation workflows. These partnerships aim to increase the adoption of automated synthesis in drug discovery and vaccine development.
Risk Factors for Investors
Investing in TBIO stock carries substantial risks that are characteristic of the OTC market:
- Liquidity Risk: OTC stocks often have lower trading volumes, making it difficult to buy or sell large positions without impacting the price.
- Financial Reporting: Companies on the OTC Pink sheets may have less stringent reporting requirements compared to those on the Nasdaq.
- Cash Burn: Like many biotech firms, Telesis Bio has a high cash burn rate, requiring constant capital to fund operations and technological development.
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Future Outlook
The future of Telesis Bio depends heavily on its ability to restructure its debt, secure further funding, or find a strategic acquirer interested in its intellectual property and BioXp™ platform. While its technology remains influential in synthetic biology, its financial standing remains a cautionary tale of the capital-intensive nature of biotech innovation.

















